Periodic depression refers to recurring episodes of depression that come and go, with symptoms of sadness, hopelessness, and a loss of interest in activities, and periods of relief in between. It is not a formal diagnosis itself, but a description that can apply to conditions like seasonal affective disorder (SAD), premenstrual dysphoric disorder (PMDD), or the depressive phases of bipolar disorder. It can also be referred to as recurrent or cyclical depression. 
 
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